Glucosamine and chondroitin are part of normal cartilage. Cartilage acts as a cushion between the bones in a joint. Glucosamine, also called chitosamine, is a natural substance that is found in the covering of shellfish. … Glucosamine may be taken separately as a dietary supplement for joints. hyaluronic acid does do is moisturize, Helps Reduce Wrinkles, Treats Sores, Sunburns and Wounds, Sorta. It’s a humectant, which means it draws water to the skin and helps prevent moisture loss, Lubricates Achy Joints, Helps Reduce Dry Eyes and Eye Discomfort & also work for Joint pain. Diacerein. also known as diacetylrhein, is a slow-acting medicine of the class anthraquinone used to treat joint diseases such as osteoarthritis (swelling and pain in the joints). Collagen Peptide does this by fortifying your blood vessels to improve their circulation throughout the body. Collagen is required by the body to mend and rebuild connective tissue damage which helps maintain healthy muscles, skin, and joints. It also strengthens the structure of bones, tendons, cartilage, and ligaments.